CPB2 Polyclonal Antibody

Catalog Number:

28311

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q96IY4
NCBI Gene ID:1361

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human CPB2 (NP_001863.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

IHC

Background:

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.

References:

appl_detail:

IHC 1:50 - 1:200

Datasheet PDF