Product Datasheet  
CPB2 Polyclonal Antibody  
Catalog Number: 28311  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q96IY4
    NCBI Gene ID:1361
  • Form of Antibody:  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant fusion protein of human CPB2 (NP_001863.2).
  • reactivity:  
  • Human,Mouse
  • appl_detail:  
  • IHC 1:50 - 1:200
  • other_names:  
  • CPB2; CPU; PCPB; TAFI; carboxypeptidase B2
  • Purification:  
  • Affinity purification
  • Specificity:  
  • Applications:  
  • IHC
  • Background:  
  • Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Alternate splicing results in multiple transcript variants.



 
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