Ataxin 3 Polyclonal Antibody

Catalog Number:

27857

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:P54252
NCBI Gene ID:4287

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human Ataxin 3 (NP_004984.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF