Product Datasheet  
Ataxin 3 Polyclonal Antibody  
Catalog Number: 27857  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P54252
    NCBI Gene ID:4287
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human Ataxin 3 (NP_004984.2).
  • reactivity：  
  • Hu,Ms
  • appl_detail：  
  • WB 1:500 - 1:2000
    IF 1:50 - 1:200
  • other_names：  
  • ATXN3; AT3; ATX3; JOS; MJD; MJD1; SCA3; ataxin-3
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IF
  • Background：  
  • Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder. The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease. There is a negative correlation between the age of onset and CAG repeat numbers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.



 
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