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Home > products > CD3E Antigen Rabbit Polyclonal Antibody

CD3E Antigen Rabbit Polyclonal Antibody

Catalog Number:

27696
other_names: CD3E;IMD18;T3E;TCRE;CD3e molecule

Amount:

100μg
calculated_mw: 23kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss Prot:P07766
GeneID:916

Form of Antibody:

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage/Stability:

Immunogen:

A synthetic peptide of human CD3E Antigen (NP_000724.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

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