Product Datasheet  
CD3E Antigen Rabbit Polyclonal Antibody  
Catalog Number: 27696  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss Prot:P07766
    GeneID:916
  • Form of Antibody：  
  • Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
  • Storage：  
  • Store at -20˚C. Avoid freeze / thaw cycles.
  • Immunogen：  
  • A synthetic peptide of human CD3E Antigen (NP_000724.1).
  • reactivity：  
  • Human,Mouse,Rat
  • appl_detail：  
  • WB 1:500 - 1:2000
    IHC 1:50 - 1:200
    IF 1:50 - 1:200
  • other_names：  
  • CD3E;IMD18;T3E;TCRE;CD3e molecule
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IHC,IF
  • Background：  

  • The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.




 
© Signalway Biotechnology All Rights Reserved.