ARAP2 Polyclonal Antibody

Catalog Number:

27664

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q8WZ64
NCBI Gene ID:116984

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human ARAP2 (NP_056045.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF