product datasheet
arap2 polyclonal antibody
catalog number: 27664
technical:tech@swbio.com
information:info@swbio.com
description
- swiss-prot no.:
- swiss-prot#:q8wz64
ncbi gene id:116984
- form of antibody:
- avoid freeze / thaw cycles.|buffer: pbs with 50% glycerol, ph7.4.
- immunogen:
- recombinant fusion protein of human arap2 (np_056045.2).
- appl_detail:
- wb 1:500 - 1:2000
- other_names:
- arap2; centd1; parx; arfgap with rhogap domain, ankyrin repeat and ph domain 2
- purification:
- affinity purification
- background:
- the protein encoded by this gene contains arf-gap, rho-gap, ankyrin repeat, ras-associating, and pleckstrin homology domains. the protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent arf6 gap that binds rhoa-gtp, but it lacks the predicted catalytic arginine in the rho-gap domain and does not have rho-gap activity. the protein associates with focal adhesions and functions downstream of rhoa to regulate focal adhesion dynamics.
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