Product Datasheet
ARAP2 Polyclonal Antibody
Catalog Number: 27664
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8WZ64
NCBI Gene ID:116984
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human ARAP2 (NP_056045.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- ARAP2; CENTD1; PARX; ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics.
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