1-832-868-1888
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Catalog Number: |
27304 |
other_names: | SMG6; C17orf31; EST1A; SMG-6; hSMG5/7a; telomerase-binding protein EST1A |
Amount: |
100μg |
calculated_mw: | 210kDa |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:Q86US8 |
Form of Antibody: |
Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4. |
Storage/Stability: |
|
Immunogen: |
Recombinant fusion protein of human SMG6 (NP_060045.4). |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described. |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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