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SMG6 Polyclonal Antibody

Catalog Number:

27304
other_names: SMG6; C17orf31; EST1A; SMG-6; hSMG5/7a; telomerase-binding protein EST1A

Amount:

100μg
calculated_mw: 210kDa
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q86US8
NCBI Gene ID:23293

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human SMG6 (NP_060045.4).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.

References:

appl_detail:

WB 1:500 - 1:2000

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