Product Datasheet  
SMG6 Polyclonal Antibody  
Catalog Number: 27304  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q86US8
    NCBI Gene ID:23293
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human SMG6 (NP_060045.4).
  • reactivity：  
  • Human,Rat
  • appl_detail：  
  • WB 1:500 - 1:2000
  • other_names：  
  • SMG6; C17orf31; EST1A; SMG-6; hSMG5/7a; telomerase-binding protein EST1A
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • This gene encodes a component of the telomerase ribonucleoprotein complex responsible for the replication and maintenance of chromosome ends. The encoded protein also plays a role in the nonsense-mediated mRNA decay (NMD) pathway, providing the endonuclease activity near the premature translation termination codon that is needed to initiate NMD. Alternatively spliced transcript variants encoding distinct protein isoforms have been described.



 
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