IKBKAP Polyclonal Antibody

Catalog Number:

27298

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:O95163
NCBI Gene ID:8518

Form of Antibody:

Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.

Storage/Stability:

Immunogen:

Recombinant fusion protein of human IKBKAP (NP_003631.2).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.

References:

appl_detail:

WB 1:1000 - 1:4000

Datasheet PDF