Product Datasheet  
IKBKAP Polyclonal Antibody  
Catalog Number: 27298  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:O95163
    NCBI Gene ID:8518
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human IKBKAP (NP_003631.2).
  • reactivity：  
  • Human,Mouse,Rat
  • appl_detail：  
  • WB 1:1000 - 1:4000
  • other_names：  
  • IKBKAP; DYS; ELP1; FD; IKAP; IKI3; TOT1; elongator complex protein 1
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • The protein encoded by this gene is a scaffold protein and a regulator for three different kinases involved in proinflammatory signaling. The encoded protein can bind NF-kappa-B-inducing kinase and I-kappa-B kinases through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia. Alternative splicing results in multiple transcript variants encoding different isoforms.



 
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