SLAMF1 Antibody

Catalog Number:

25284

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q13291
Gene ID:6504

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide near the amino terminus of human SLAMF1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Two isoforms of SLAMF1 are known to exist; this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.

Applications:

ELISA WB

Background:

The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).

References:

appl_detail:

Datasheet PDF