Product Datasheet  
SLAMF1 Antibody  
Catalog Number: 25284  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:Q13291
    Gene ID:6504
  • Form of Antibody:  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage:  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen:  
  • Raised against a 15 amino acid peptide near the amino terminus of human SLAMF1.
  • reactivity:  
  • Hu Ms Rt
  • appl_detail:  
  • other_names:  
  • Signaling lymphocytic activation molecule family member 1, CD150, CDw150, IPO-3, SLAM
  • Purification:  
  • Affinity chromatography purified via peptide column
  • Specificity:  
  • Two isoforms of SLAMF1 are known to exist; this antibody will recognize both isoforms. SLAMF1 antibody is predicted to not cross-react with other SLAM protein family members.
  • Applications:  
  • ELISA WB
  • Background:  
  • The signaling lymphocyte-activation molecule family member 1 (SLAMF1) is a novel receptor on T cells that potentiates T cell expansion in a CD28-independent manner. SLAMF1 is predominantly expressed by hematopoietic tissues. Reports suggest that the extracellular domain of SLAMF1 is the receptor for the measles virus and acts as a co-activator on both T and B cells. It is thought to interact with SH2D1A and with PTPN11 via its cytoplasmic domain. Mutations of the SLAM associated gene may be associated with X-linked lympho-proliferative disease (XLP).



 
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