LASS6 Antibody

Catalog Number:

24802

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q6ZMG9
Gene ID:253782

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 13 amino acid peptide near the amino terminus of the human LASS6.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.

Applications:

ELISA WB IHC

Background:

The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development.

References:

appl_detail:

Datasheet PDF