Product Datasheet  
LASS6 Antibody  
Catalog Number: 24802  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot:Q6ZMG9
    Gene ID:253782
  • Form of Antibody：  
  • Supplied in PBS containing 0.02% sodium azide.
  • Storage：  
  • Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Immunogen：  
  • Raised against a 13 amino acid peptide near the amino terminus of the human LASS6.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  
  • other_names：  
  • Longevity Assurance Homolog 6, LAG1 homolog 6
  • Purification：  
  • Affinity chromatography purified via peptide column
  • Specificity：  
  • At least two isoforms of LASS6 are known to exist. This antibody is predicted not to cross-react with LASS5.
  • Applications：  
  • ELISA WB IHC
  • Background：  
  • The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation. Like the highly homologous LASS5, LASS6 is also an endoplasmic reticulum, multi-pass membrane protein. LASS6 is also involved in the synthesis of C14, C16 and C18-ceramide, but shows a preference for unsaturated fatty acids. LASS6 is broadly expressed in a wide range of tissues and microarray data suggests that it may play a role in cancer differentiation and early embryonic development.



 
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