eIF4E Rabbit mAb

Catalog Number:

77788

Amount:

100μg

Price:

$318

Swiss-Prot No:

P06730

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human eIF4E

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IP

Background:

The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

References:

appl_detail:

WB 1:500 - 1:2000
IP 1:50 - 1:200

Datasheet PDF