Product Datasheet  
eIF4E Rabbit mAb  
Catalog Number: 77788  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • P06730
  • Form of Antibody：  
  • Storage：  
  • Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
  • Immunogen：  
  • A synthesized peptide derived from human eIF4E
  • reactivity：  
  • Mouse,Rat
  • appl_detail：  
  • WB 1:500 - 1:2000
    IP 1:50 - 1:200
  • other_names：  
  • AUTS19;CBP;EIF4E1;EIF4EL1;EIF4F;eIF-4E;EIF4E
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IP
  • Background：  
  • The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]



 
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