CD86 Rabbit mAb

Catalog Number:

77580

Amount:

100μg

Price:

$318

Swiss-Prot No:

P42081

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human CD86

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF