1-832-206-4069
order@swbio.com
.jpg)
catalog number: |
77580 |
| other_names: | b7-2;b7.2;b70;cd28lg2;lab72;cd86 |
amount: |
100μg |
| calculated_mw: | 70kda |
| host_species: | rabbit |
price: |
$318 |
swiss-prot no: |
p42081 |
form of antibody: |
|
storage/stability: |
|
immunogen: |
a synthesized peptide derived from human cd86 |
purification: |
affinity purification |
specificity/sensitivity: |
|
applications: |
wb |
background: |
this gene encodes a type i membrane protein that is a member of the immunoglobulin superfamily. this protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of t cells, cd28 antigen and cytotoxic t-lymphocyte-associated protein 4. binding of this protein with cd28 antigen is a costimulatory signal for activation of the t-cell. binding of this protein with cytotoxic t-lymphocyte-associated protein 4 negatively regulates t-cell activation and diminishes the immune response. alternative splicing results in several transcript variants encoding different isoforms.[provided by refseq, may 2011] |
references: |
|
appl_detail: |
wb 1:500 - 1:2000 |
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