product datasheet
cd86 rabbit mab
catalog number: 77580
technical:tech@swbio.com
information:info@swbio.com
description
- storage:
- store at -20℃. avoid freeze / thaw cycles.|buffer: pbs with 0.02% sodium azide,0.05% bsa,50% glycerol,ph7.3.
- immunogen:
- a synthesized peptide derived from human cd86
- reactivity:
- human,mouse,rat
- appl_detail:
- wb 1:500 - 1:2000
- other_names:
- b7-2;b7.2;b70;cd28lg2;lab72;cd86
- purification:
- affinity purification
- background:
- this gene encodes a type i membrane protein that is a member of the immunoglobulin superfamily. this protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of t cells, cd28 antigen and cytotoxic t-lymphocyte-associated protein 4. binding of this protein with cd28 antigen is a costimulatory signal for activation of the t-cell. binding of this protein with cytotoxic t-lymphocyte-associated protein 4 negatively regulates t-cell activation and diminishes the immune response. alternative splicing results in several transcript variants encoding different isoforms.[provided by refseq, may 2011]
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