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home > products > [ko validated] c-myc rabbit mab

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catalog number:

77520
other_names: mrtl;mycc;bhlhe39;c-myc;myc

amount:

100μg
calculated_mw: 57kda
host_species: rabbit

price:

$318

swiss-prot no:

p01106

form of antibody:

storage/stability:

immunogen:

immunogen:

a synthesized peptide derived from human c-myc

purification:

affinity purification

specificity/sensitivity:

applications:

wb,if,chip

background:

background:

the protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. it functions as a transcription factor that regulates transcription of specific target genes. mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including burkitt lymphoma. there is evidence to show that alternative translation initiations from an upstream, in-frame non-aug (cug) and a downstream aug start site result in the production of two isoforms with distinct n-termini. the synthesis of non-aug initiated protein is suppressed in burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by refseq, jul 2008]

references:

appl_detail:

wb 1:500 - 1:2000
if 1:50 - 1:200
chip 1:50 - 1:200

datasheet pdf

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