1-832-206-4069
order@swbio.com
catalog number: |
77520 |
|
other_names: | mrtl;mycc;bhlhe39;c-myc;myc | |
amount: |
100μg |
|
calculated_mw: | 57kda | |
host_species: | rabbit | |
price: |
$318 |
|
swiss-prot no: |
p01106 |
|
form of antibody: |
||
storage/stability: |
||
immunogen: |
immunogen: |
a synthesized peptide derived from human c-myc |
purification: |
affinity purification |
|
specificity/sensitivity: |
||
applications: |
wb,if,chip |
|
background: |
background: |
the protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. it functions as a transcription factor that regulates transcription of specific target genes. mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including burkitt lymphoma. there is evidence to show that alternative translation initiations from an upstream, in-frame non-aug (cug) and a downstream aug start site result in the production of two isoforms with distinct n-termini. the synthesis of non-aug initiated protein is suppressed in burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by refseq, jul 2008] |
references: |
||
appl_detail: |
wb 1:500 - 1:2000 |
|
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