product datasheet
[ko validated] c-myc rabbit mab
catalog number: 77520
technical:tech@swbio.com
information:info@swbio.com
description
- storage:
- store at -20℃. avoid freeze / thaw cycles.|buffer: pbs with 0.02% sodium azide,0.05% bsa,50% glycerol,ph7.3.
- immunogen:
- a synthesized peptide derived from human c-myc
- appl_detail:
- wb 1:500 - 1:2000
if 1:50 - 1:200
chip 1:50 - 1:200
- other_names:
- mrtl;mycc;bhlhe39;c-myc;myc
- purification:
- affinity purification
- background:
- the protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. it functions as a transcription factor that regulates transcription of specific target genes. mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including burkitt lymphoma. there is evidence to show that alternative translation initiations from an upstream, in-frame non-aug (cug) and a downstream aug start site result in the production of two isoforms with distinct n-termini. the synthesis of non-aug initiated protein is suppressed in burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by refseq, jul 2008]
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