NBS1/NBN Rabbit mAb

Catalog Number:

77391

Amount:

100μg

Price:

$318

Swiss-Prot No:

O60934

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human NBS1/NBN

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF