Product Datasheet
NBS1/NBN Rabbit mAb
Catalog Number: 77391
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Storage:
- Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
- Immunogen:
- A synthesized peptide derived from human NBS1/NBN
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- AT-V1, AT-V2, ATV, NBS, NBS1, P95
- Purification:
- Affinity purification
- Background:
- Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]
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