Phospho-BRD4-S1083 Rabbit mAb

Catalog Number:

77377

Amount:

100μg

Price:

$318

Swiss-Prot No:

O60885

Form of Antibody:

Storage/Stability:

Immunogen:

A synthetic peptide corresponding to a sequence within amino acids 1050 to 1150 of human Phospho-BRD4-S1083 (NP_490597.1).

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF