Product Datasheet
Phospho-BRD4-S1083 Rabbit mAb
Catalog Number: 77377
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Storage:
- Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
- Immunogen:
- A synthetic peptide corresponding to a sequence within amino acids 1050 to 1150 of human Phospho-BRD4-S1083 (NP_490597.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- BRD4; CAP; HUNK1; HUNKI; MCAP; bromodomain containing 4
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15;19)(q13;p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.
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