TUG/ASPSCR1 Rabbit mAb

Catalog Number:

77371

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q9BZE9

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human TUG/ASPSCR1.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF