Product Datasheet  
TUG/ASPSCR1 Rabbit mAb  
Catalog Number: 77371  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Q9BZE9
  • Form of Antibody：  
  • Storage：  
  • Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
  • Immunogen：  
  • A synthesized peptide derived from human TUG/ASPSCR1.
  • reactivity：  
  • Human,Mouse
  • appl_detail：  
  • WB 1:500 - 1:2000
  • other_names：  
  • ASPSCR1; ASPCR1; ASPL; ASPS; RCC17; TUG; UBXD9; UBXN9; tether containing UBX domain for GLUT4
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.



 
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