Product Datasheet
OSGIN1 Polyclonal Antibody
Catalog Number: 29442
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9UJX0
NCBI Gene ID:29948
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human OSGIN1 (NP_892026.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- OSGIN1; BDGI; OKL38; oxidative stress-induced growth inhibitor 1
- Purification:
- Affinity purification
- Background:
- This gene encodes an oxidative stress response protein that regulates cell death. Expression of the gene is regulated by p53 and is induced by DNA damage. The protein regulates apoptosis by inducing cytochrome c release from mitochondria. It also appears to be a key regulator of both inflammatory and anti-inflammatory molecules. The loss of this protein correlates with uncontrolled cell growth and tumor formation. Naturally occurring read-through transcription exists between this gene and the neighboring upstream malonyl-CoA decarboxylase (MLYCD) gene, but the read-through transcripts are unlikely to produce a protein product.
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