Product Datasheet
PHC2 Polyclonal Antibody
Catalog Number: 28686
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8IXK0
NCBI Gene ID:1912
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human PHC2 (NP_004418.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- PHC2; EDR2; HPH2; PH2; polyhomeotic homolog 2
- Purification:
- Affinity purification
- Background:
- In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.
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