Product Datasheet
GGT5 Polyclonal Antibody
Catalog Number: 28537
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P36269
NCBI Gene ID:2687
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human GGT5 (NP_001093251.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- GGT5; GGL; GGT 5; GGT-REL; GGTLA1; gamma-glutamyltransferase 5
- Purification:
- Affinity purification
- Background:
- This gene is a member of the gamma-glutamyl transpeptidase gene family, and some reports indicate that it is capable of cleaving the gamma-glutamyl moiety of glutathione. The protein encoded by this gene is synthesized as a single, catalytically-inactive polypeptide, that is processed post-transcriptionally to form a heavy and light subunit, with the catalytic activity contained within the small subunit. The encoded enzyme is able to convert leukotriene C4 to leukotriene D4, but appears to have distinct substrate specificity compared to gamma-glutamyl transpeptidase. Alternative splicing results in multiple transcript variants encoding different isoforms.
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