Product Datasheet
SUMF1 Polyclonal Antibody
Catalog Number: 28494
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8NBK3
NCBI Gene ID:285362
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human SUMF1 (NP_877437.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- SUMF1; AAPA3037; FGE; UNQ3037; sulfatase-modifying factor 1
- Purification:
- Affinity purification
- Background:
- This gene encodes an enzyme that catalyzes the hydrolysis of sulfate esters by oxidizing a cysteine residue in the substrate sulfatase to an active site 3-oxoalanine residue, which is also known as C-alpha-formylglycine. Mutations in this gene cause multiple sulfatase deficiency, a lysosomal storage disorder. Alternative splicing results in multiple transcript variants.
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