Product Datasheet
FMO2 Polyclonal Antibody
Catalog Number: 28412
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q99518
NCBI Gene ID:2327
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human FMO2 (NP_001451.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- FMO2; FMO1B1; flavin containing monooxygenase 2
- Purification:
- Affinity purification
- Background:
- This gene encodes a flavin-containing monooxygenase family member. It is an NADPH-dependent enzyme that catalyzes the N-oxidation of some primary alkylamines through an N-hydroxylamine intermediate. However, some human populations contain an allele (FMO2*2A) with a premature stop codon, resulting in a protein that is C-terminally-truncated, has no catalytic activity, and is likely degraded rapidly. This gene is found in a cluster with other related family members on chromosome 1. Alternative splicing results in multiple transcript variants.
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