Product Datasheet
RNASEH2C Polyclonal Antibody
Catalog Number: 28396
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8TDP1
NCBI Gene ID:84153
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human RNASEH2C (NP_115569.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- RNASEH2C; AGS3; AYP1; ribonuclease H2 subunit C
- Purification:
- Affinity purification
- Background:
- This gene encodes a ribonuclease H subunit that can cleave ribonucleotides from RNA:DNA duplexes. Mutations in this gene cause Aicardi-Goutieres syndrome-3, a disease that causes severe neurologic dysfunction. A pseudogene for this gene has been identified on chromosome Y, near the sex determining region Y (SRY) gene.
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