Product Datasheet
IDI1 Polyclonal Antibody
Catalog Number: 28367
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13907
NCBI Gene ID:3422
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human IDI1 (NP_004499.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- IDI1; IPP1; IPPI1; isopentenyl-diphosphate Delta-isomerase 1
- Purification:
- Affinity purification
- Background:
- IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity.
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