Product Datasheet
AP3B2 Polyclonal Antibody
Catalog Number: 28357
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13367
NCBI Gene ID:8120
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human AP3B2 (NP_004635.2).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- AP3B2; EIEE48; NAPTB; AP-3 complex subunit beta-2
- Purification:
- Affinity purification
- Background:
- Adaptor protein complex 3 (AP-3 complex) is a heterotrimeric protein complex involved in the formation of clathrin-coated synaptic vesicles. The protein encoded by this gene represents the beta subunit of the neuron-specific AP-3 complex and was first identified as the target antigen in human paraneoplastic neurologic disorders. The encoded subunit binds clathrin and is phosphorylated by a casein kinase-like protein, which mediates synaptic vesicle coat assembly. Defects in this gene are a cause of early-onset epileptic encephalopathy.
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