Product Datasheet
CD127 Polyclonal Antibody
Catalog Number: 28305
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P16871
NCBI Gene ID:3575
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human CD127 (NP_002176.2).
- appl_detail:
- WB 1:500 - 1:2000
IP 1:50 - 1:100
- other_names:
- IL7R; CD127; CDW127; IL-7R-alpha; IL7RA; ILRA; interleukin 7 receptor
- Purification:
- Affinity purification
- Background:
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found.
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