Product Datasheet
GNAI3 Polyclonal Antibody
Catalog Number: 27977
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P08754
NCBI Gene ID:2773
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human GNAI3 (NP_006487.1).
- appl_detail:
- WB 1:500 - 1:2000
IP 1:50 - 1:100
- other_names:
- GNAI3; 87U6; ARCND1; G protein subunit alpha i3
- Purification:
- Affinity purification
- Background:
- Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.
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