Product Datasheet
DYNC2H1 Polyclonal Antibody
Catalog Number: 27910
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8NCM8
NCBI Gene ID:79659
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human DYNC2H1 (NP_001073932.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- DYNC2H1; ATD3; DHC1b; DHC2; DNCH2; DYH1B; SRPS2B; SRTD3; hdhc11; cytoplasmic dynein 2 heavy chain 1
- Purification:
- Affinity purification
- Background:
- This gene encodes a large cytoplasmic dynein protein that is involved in retrograde transport in the cilium and has a role in intraflagellar transport, a process required for ciliary/flagellar assembly. Mutations in this gene cause a heterogeneous spectrum of conditions related to altered primary cilium function and often involve polydactyly, abnormal skeletogenesis, and polycystic kidneys. Alternative splicing results in multiple transcript variants encoding distinct proteins.
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