Product Datasheet
AADAT Polyclonal Antibody
Catalog Number: 27893
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q8N5Z0
NCBI Gene ID:51166
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human AADAT (NP_001273611.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- AADAT; KAT2; KATII; KYAT2; aminoadipate aminotransferase
- Purification:
- Affinity purification
- Background:
- This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene.
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