Product Datasheet
KCNIP3 Polyclonal Antibody
Catalog Number: 28317
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y2W7
NCBI Gene ID:30818
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- A synthetic peptide of human KCNIP3 (NP_038462.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- KCNIP3; CSEN; DREAM; KCHIP3; calsenilin
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.
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