Product Datasheet  
SORL1 Polyclonal Antibody  
Catalog Number: 27871  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q92673
    NCBI Gene ID:6653
  • Form of Antibody:  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant fusion protein of human SORL1 (NP_003096.1).
  • reactivity:  
  • Human
  • appl_detail:  
  • WB 1:500 - 1:2000
  • other_names:  
  • SORL1; C11orf32; LR11; LRP9; SORLA; SorLA-1; gp250; sortilin-related receptor
  • Purification:  
  • Affinity purification
  • Specificity:  
  • Applications:  
  • WB
  • Background:  
  • This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease.



 
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