Product Datasheet
EHD2 Polyclonal Antibody
Catalog Number: 27853
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9NZN4
NCBI Gene ID:30846
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human EHD2 (NP_055416.2).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:1000 - 1:3000
- other_names:
- EHD2; PAST2; EH domain containing 2
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the EH domain-containing protein family. These proteins are characterized by a C-terminal EF-hand domain, a nucleotide-binding consensus site at the N terminus and a bipartite nuclear localization signal. The encoded protein interacts with the actin cytoskeleton through an N-terminal domain and also binds to an EH domain-binding protein through the C-terminal EH domain. This interaction appears to connect clathrin-dependent endocytosis to actin, suggesting that this gene product participates in the endocytic pathway.
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