Product Datasheet
ICE2 Polyclonal Antibody
Catalog Number: 27824
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q659A1
NCBI Gene ID:79664
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human ICE2 (NP_078887.2).
- appl_detail:
- WB 1:500 - 1:1000
- other_names:
- ICE2; BRCC1; NARG2; little elongation complex subunit 2
- Purification:
- Affinity purification
- Background:
- This gene encodes a protein component of the little elongation complex (LEC), which plays a role in small nuclear RNA (snRNA) transcription. The LEC regulates snRNA transcription by enhancing both RNA Polymerase II occupancy and transcriptional elongation. The encoded protein and other LEC components have been shown to localize to Cajal bodies, which are sites of ribonucleoprotein (RNP) complex assembly. Pseudogenes of this gene have been identified on chromosomes 3 and 4.
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