Product Datasheet
MBNL2 Polyclonal Antibody
Catalog Number: 27808
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q5VZF2
NCBI Gene ID:10150
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human MBNL2 (NP_659002.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- MBNL2; MBLL; MBLL39; PRO2032; muscleblind-like protein 2
- Purification:
- Affinity purification
- Background:
- This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
© Signalway Biotechnology All Rights Reserved.