Product Datasheet
CDK11B Polyclonal Antibody
Catalog Number: 27804
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P21127
NCBI Gene ID:984
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human CDK11B (NP_277021.2).
- appl_detail:
- WB 1:500 - 1:2000
IF 1:50 - 1:200
- other_names:
- CDK11B; CDC2L1; CDK11; CDK11-p110; CDK11-p46; CDK11-p58; CLK-1; PITSLREA; PK58; p58; p58CDC2L1; p58CLK-1; cyclin-dependent kinase 11B
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, this gene shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. The protein kinase encoded by this gene can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.
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