Product Datasheet
WDR35 Polyclonal Antibody
Catalog Number: 27800
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9P2L0
NCBI Gene ID:57539
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human WDR35 (NP_065830.2).
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- WB 1:500 - 1:1000
IF 1:50 - 1:200
- other_names:
- WDR35; CED2; IFT121; IFTA1; SRTD7; WD repeat domain 35
- Purification:
- Affinity purification
- Background:
- This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Two patients with Sensenbrenner syndrome / cranioectodermal dysplasia (CED) were identified with mutations in this gene, consistent with a possible ciliary function.
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