Product Datasheet
LMO2 Polyclonal Antibody
Catalog Number: 27755
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P25791
NCBI Gene ID:4005
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human LMO2 (NP_001135788.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- LMO2; RBTN2; RBTNL1; RHOM2; TTG2; rhombotin-2
- Purification:
- Affinity purification
- Background:
- LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.
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