Product Datasheet
PHF5A Polyclonal Antibody
Catalog Number: 27754
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q7RTV0
NCBI Gene ID:84844
- Form of Antibody:
- Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
- Immunogen:
- Recombinant fusion protein of human PHF5A (NP_116147.1).
- appl_detail:
- WB 1:500 - 1:2000
- other_names:
- PHF5A; INI; Rds3; SAP14b; SF3B7; SF3b14b; bK223H9.2; PHD finger protein 5A
- Purification:
- Affinity purification
- Background:
- This gene encodes a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.
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