Product Datasheet  
PI3 Polyclonal Antibody  
Catalog Number: 27702  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P19957
    NCBI Gene ID:5266
  • Form of Antibody：  
  • Avoid freeze / thaw cycles.|Buffer: PBS with 50% glycerol, pH7.4.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant fusion protein of human PI3 (NP_002629.1).
  • reactivity：  
  • Human,Rat
  • appl_detail：  
  • IHC 1:50 - 1:200
  • other_names：  
  • PI3; ESI; SKALP; WAP3; WFDC14; cementoin; elafin
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • IHC
  • Background：  
  • This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.



 
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